tag:blogger.com,1999:blog-1078685116296921818.post5646008301595499500..comments2023-04-26T09:15:19.142-04:00Comments on CFS Central: DR. ILA SINGH:Mindy Kiteihttp://www.blogger.com/profile/12570126270241201680noreply@blogger.comBlogger36125tag:blogger.com,1999:blog-1078685116296921818.post-42649258985131888432011-05-08T10:37:56.003-04:002011-05-08T10:37:56.003-04:00I am waiting to see what the Canadian studies say ...I am waiting to see what the Canadian studies say to help evaluate the debate on XMRV and I will go from there. Please report on these studies when they are published Mindy. For me, they will keep the XMRV door open or close it.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-1078685116296921818.post-83130018085459993182011-05-08T06:52:28.130-04:002011-05-08T06:52:28.130-04:00Singh keeps telling people it's a different vi...Singh keeps telling people it's a different virus in prostate cancer patients, not XMRV. If her samples don't contain XMRV then they cannot be used as a control, and this all contradicts what is said in Shin et al.<br /><br />V99Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-1078685116296921818.post-37617703253569340312011-05-07T19:26:58.097-04:002011-05-07T19:26:58.097-04:00I'm quite certain the commenters mentioning &q...I'm quite certain the commenters mentioning "attacks" on Dr Singh are not referring to the many reasonable comments here containing valid questions and criticisms regarding Singh's methods, but rather those spouting conspiracy theories, accusing her of being bought off, etc. Look at the very first comment, for example, accusing her of having "succumbed to political or Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-1078685116296921818.post-57044393313849792992011-05-07T17:05:51.617-04:002011-05-07T17:05:51.617-04:00Singh, Light, Bateman et al vastly overstepped whe...Singh, Light, Bateman et al vastly overstepped when they concluded that their study indicates people like Dr Snyderman and Dr Deckoff-Jones shouldn't be trying antiretroviral drugs. Their study hasn't the capacity to come to such conclusions, so I have to wonder why they even spoke to the issue. <br /><br />There is so much research out there that shows HGRVs like XMRV and the MLVs are oerganixhttps://www.blogger.com/profile/12870957662833413723noreply@blogger.comtag:blogger.com,1999:blog-1078685116296921818.post-91238203885266273312011-05-07T16:08:00.216-04:002011-05-07T16:08:00.216-04:00It is not a knock on the Lights either to question...It is not a knock on the Lights either to question the effectiveness of these new assays. Alan Light is a professor of anesthesiology not a retrovirologist. So Retrovirology and viral assays are not really his area of expertise.<br /> I admire Dr. Light and know he wants to help ME-CFS patients but again he is not a retrovirologist or a virologist. So he may have tried everything he could thinkAnonymousnoreply@blogger.comtag:blogger.com,1999:blog-1078685116296921818.post-69600190257301231892011-05-07T15:16:04.185-04:002011-05-07T15:16:04.185-04:00The commenters accusing other commenters of "...The commenters accusing other commenters of "attacking" Dr. Singh are spewing logical fallacies all over the place. In just a few words they've used ad hominem, appeal to authority, red herring, and straw man fallacies rather than attempting to address legitimate criticisms.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-1078685116296921818.post-91390751113372754052011-05-07T14:00:25.220-04:002011-05-07T14:00:25.220-04:00I wonder if it would be possible for Dr. Mikovits ...I wonder if it would be possible for Dr. Mikovits to go into someone's lab and show them how to find the virus. Could she demonstrate? Why not go into the lab at the NIH, draw the blood of someone proven to be positive and show them XMRV. I don't understand why that can't happen. It would only take one sample. Then, they could see how to do it and that it was there and all the Patnoreply@blogger.comtag:blogger.com,1999:blog-1078685116296921818.post-64130146771806814492011-05-07T13:31:16.164-04:002011-05-07T13:31:16.164-04:00I agree we should not be attacking Singh here. Sh...I agree we should not be attacking Singh here. She had all the best intentions, and did what she feels was as thorough a study as possible. It's disappointing, for sure -- but we can't attack everyone who doesn't find what we want them to find. <br /><br />We are all frustrated as we are all so severely ill and this pushes us that much farther from a cure, but we can't blame Dr.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-1078685116296921818.post-18164570382147225372011-05-07T13:29:46.534-04:002011-05-07T13:29:46.534-04:00I am rather perturbed at the number of times vario...I am rather perturbed at the number of times various people are writing-off XMRV as being in association with ME/CFS, when none of the experimental data suggests such a positive conclusion. The titles of the articles go beyond the deductions possible from the experiments. To me, this is a bit sinister, as in "methinks the lady doth protest too much". <br /><br />Seriously, setting asideLaurence Swifthttp://www.laurenceswift.co.uknoreply@blogger.comtag:blogger.com,1999:blog-1078685116296921818.post-79668386548084301672011-05-07T13:19:58.145-04:002011-05-07T13:19:58.145-04:00Thank you Mindy for asking the right questions.
H...Thank you Mindy for asking the right questions.<br /><br />HIV was only discovered when Dr Luc Montagnier found a virus in a Lymph node biopsy of a patient.<br /><br />Researchers from different countries had been looking in the blood of patients with no success. It took time to develop the rights tests.<br /><br />It's not unreasonable to assume that different techniques return different Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-1078685116296921818.post-86853498675837081382011-05-07T12:57:47.883-04:002011-05-07T12:57:47.883-04:00I don't believe that respectful questions, exp...I don't believe that respectful questions, expressions of doubt, or requests for clarification constitute any sort of attack on Dr. Singh. In a spirit of respectful inquiry then, I do want to know what would explain detection of antibodies to XMRV via serology, in a "CFS" diagnosed patient like my 17-year-old. In a recent exchange on Twitter, Dr. Racaniello suggested that what were Creekhttps://www.blogger.com/profile/06145185297188783266noreply@blogger.comtag:blogger.com,1999:blog-1078685116296921818.post-75533358771680659262011-05-07T12:38:26.912-04:002011-05-07T12:38:26.912-04:00"To the people attacking Singh, this is crazy..."To the people attacking Singh, this is crazy."<br /><br />I agree. It's also incredibly hypocritical, as most of those attacking her, were praising her up until this negative study came out.<br /><br />These attacks are also an insult to the Lights, who have a friend who DIED from CFS/ME.<br /><br />Sheesh.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-1078685116296921818.post-67424222228193215052011-05-07T11:39:36.501-04:002011-05-07T11:39:36.501-04:00Lipkin seems a real scientist.
"We have a pl...Lipkin seems a real scientist. <br />"We have a plethora of explanations for how CFS/XMRV/MLV studies could go awry. However, we don’t have evidence that they have. Absent an appropriately powered study representing blinded analyses by Mikovitz and Lo/Alter of samples from well characterized subjects using their reagents, protocols and people, all we have is more confusion."<br />http:/carlitoshttps://www.blogger.com/profile/02678863106324149504noreply@blogger.comtag:blogger.com,1999:blog-1078685116296921818.post-58666285330041132622011-05-07T10:41:22.873-04:002011-05-07T10:41:22.873-04:00Thanks to Mindy for asking the questions and to Dr...Thanks to Mindy for asking the questions and to Dr. Singh for answering them.Joanhttps://www.blogger.com/profile/15274105705391532568noreply@blogger.comtag:blogger.com,1999:blog-1078685116296921818.post-76415606667130913682011-05-07T10:30:03.697-04:002011-05-07T10:30:03.697-04:00Singh: "We are now convinced that there is no...Singh: "We are now convinced that there is no XMRV in CFS patients--so the reason for starting those drugs does not exist." <br /><br />One study would not definitively disprove the original findings.<br /><br />This would be imply that Science and PNAS were duped into publishing the WPI studies?<br /><br />Unless it is again the definitional issue, which is why CFS should be abandoned Jillhttps://www.blogger.com/profile/01316284870104429837noreply@blogger.comtag:blogger.com,1999:blog-1078685116296921818.post-22843375136448927312011-05-07T10:10:32.477-04:002011-05-07T10:10:32.477-04:00Singh's primate study found that XMRV left the...Singh's primate study found that XMRV left the blood of the infected primates after a few weeks (6, I believe). Isn't that finding plus the finding of XMRV in prostate cancer patient tissue good enough evidence to justify a study looking for XMRV/MLV in the tissues of patients with ME/CFS?<br /><br />Quote: <br /><br />CFS Central: Do you believe scientists should be looking for XMRV in 4generationsnoreply@blogger.comtag:blogger.com,1999:blog-1078685116296921818.post-61947585624240034762011-05-07T09:57:25.426-04:002011-05-07T09:57:25.426-04:00Highly accomplished researchers can miss the mark....Highly accomplished researchers can miss the mark. It's not a knock on Sighn to say it's posible her assays don't work. <br /> Again until we have multiple repication studies HGRV research in ME still remains an area of confusion at best.<br /> What needs to be done is a nmber of exact replications. Then if the same results are found the experiment needs to be done again and againAnonymousnoreply@blogger.comtag:blogger.com,1999:blog-1078685116296921818.post-35473131126937266382011-05-07T07:55:43.664-04:002011-05-07T07:55:43.664-04:00What a shame.
"Singh: Our prostate cancer st...What a shame.<br /><br />"Singh: Our prostate cancer study was entirely on prostate tissues. These were archived in tissue banks in a de-identified manner, so there was no way to go back to those patients and obtain blood samples. So, we could not test some of the new tests we developed on our material from prostate cancer patients."<br /><br />Perhaps Singh could source blinded Chris Douglasnoreply@blogger.comtag:blogger.com,1999:blog-1078685116296921818.post-6782593885712627742011-05-07T07:35:34.780-04:002011-05-07T07:35:34.780-04:00Fantastic questions Mindy. It seems that there'...Fantastic questions Mindy. It seems that there're even more unknowns and things to clarify in this study than we previously thought.inuoinmusichttps://www.blogger.com/profile/05061249870057011919noreply@blogger.comtag:blogger.com,1999:blog-1078685116296921818.post-32980537313329766952011-05-07T06:58:37.564-04:002011-05-07T06:58:37.564-04:00I have one question for Dr. Singh. She can find XM...I have one question for Dr. Singh. She can find XMRV in prostatecancer patients. Can she detect XMRV in the blood by these cancer patients? I ask this because she don't tested CVS patients in the tissue.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-1078685116296921818.post-34396000286854255922011-05-07T06:20:30.724-04:002011-05-07T06:20:30.724-04:00Great Interview Mindy!
I have to say this study ...Great Interview Mindy! <br /><br />I have to say this study has a lot of holes in it:<br /><br />-Singh found it at a background rate of 4% in controls in her prostate studies, yet found it at 0% here (suggesting her assays don't work).<br /><br />-Singh says <i>"blood is where the focus should be"</i>, yet we know that this virus is extremely difficult to find in blood, that it garciahttps://www.blogger.com/profile/03083870717305087739noreply@blogger.comtag:blogger.com,1999:blog-1078685116296921818.post-18694349375360363232011-05-07T05:33:52.199-04:002011-05-07T05:33:52.199-04:00Thanks, Mindy, for asking these important question...Thanks, Mindy, for asking these important questions. I think it's premature to claim that "XMRV not associated with CFS, comprehensive study finds" as her press release does. This is the take-home message everyone reading any news of this will get and it's overreaching. We don't know yet for sure for the reasons other commentors here have noted.Justinhttps://www.blogger.com/profile/16661093224060056052noreply@blogger.comtag:blogger.com,1999:blog-1078685116296921818.post-39809404208564606742011-05-07T04:23:44.084-04:002011-05-07T04:23:44.084-04:00I'm sorry, but if Dr. Singh can't satisfac...I'm sorry, but if Dr. Singh can't satisfactorally answer the very basic question to do with the 4% background rate, then this study is unsound and means nothing much at all.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-1078685116296921818.post-4341023517019953862011-05-07T04:07:22.634-04:002011-05-07T04:07:22.634-04:00Isn't it "funny" how there is one &q...Isn't it "funny" how there is one "person" who is very determined to paint the ME/CFS community as "crazies" every chance they get and on many blogs and forum comments sections? One could almost think there is an agenda. But then again I'm probably just being crazy. Oldest trick in the book.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-1078685116296921818.post-5492349500667950022011-05-07T04:03:39.940-04:002011-05-07T04:03:39.940-04:00Mindy, thanks for continuing to cover the CFS stor...Mindy, thanks for continuing to cover the CFS story and thanks also to Dr Singh, who is a highly reputable CFS researcher who has been working hard to get to the truth about our illness. I know that we are all desperate to find the cause for our disease but to accuse Dr Singh of not acting in good faith is ridiculous. <br /><br />I often see comments on articles like this attacking scientists Anonymousnoreply@blogger.com